GC-MS Analysis and Inhibitory Evaluation of Terminalia catappa Leaf Extracts on Major Enzymes Linked to Diabetes

Table 6

Drug-likeness violation of selected virtual screened hit compounds.

S. no	Compound	MW	Log P	HA	HD	# Lipinski violations
1	Ethyl-α-D-glucopyranoside	208.21	−2.18	6	4	—
2	n-Hexadecanoic acid	256.42	4.19	2	1	—
3	Phytol	296.53	5.25	1	1	1
4	Vitamin E	430.71	6.14	2	1	1
5	Acarbose	645.6	−6.94	19	14	3
6	Lipinski rule details	≤500	≤5	≤10	≤5

MW: molecular weight; log P: octanol-water partition coefficient; HA: hydrogen acceptor; HD: hydrogen donor.