Moxibustion of Zusanli (ST36) and Shenshu (BL23) Alleviates Cartilage Degradation through RANKL/OPG Signaling in a Rabbit Model of Rheumatoid Arthritis

Figure 2

Histological assessment cartilage degradation in control, RA, and moxibustion group. ((a) to (c)) HE staining showing the changes of articular structure, cartilage cells and tidemark integrity in control (a), RA (b), and moxibustion group (c). Black arrow indicates disordered chondrocyte. Red arrow indicates destruction of tidemark. ((d) to (f)) HE staining showing the changes of subchondral bone trabeculae in control (d), RA (e), and moxibustion group (f). Black arrow indicates disruption of bone trabecular. Magnification, × 400.

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