Development of a HPLC-MS/MS Method to Determine the 13 Elements of Semen Cuscutae and Application to a Pharmacokinetic Study in Rats

Figure 2

MRM chromatograms of 13 analytes. Quercitrin (1). Quercetin (2). Hyperoside (3). Caffeic acid (4). Rutin (5). Chlorogenic Acid (6). Luteolin (7). Apigenin (8). Kaempferol (9). Isoquercitrin (10). Cryptochlorogenic Acid (11). Isorhamnetin-3-O-glucoside (12). Astragalin (13). IS (14). (a) Blank plasma; (b) blank plasma spiked with the analytes and IS; (c) plasma sample collected at 0.25 h after oral administration of Semen Cuscutae extract.

(a)

(b)

(c)