Electroacupuncture Relieves CCI-Induced Neuropathic Pain Involving Excitatory and Inhibitory Neurotransmitters

Figure 1

EA at GV20 reduced CCI-induced mechanical and thermal pain behaviors. Animal pain behaviors were tested at days 5–8 after CCI injury (n = 12). (a) Mechanical allodynia was measured by electronic von Frey filaments (g); (b) thermal hyperalgesia (hot) was measured by radiant heat and withdrawal latency (s) is presented as the difference between injured and control sides; (c) thermal hyperalgesia (cold) was measured using a cold plate apparatus and the number of injured hind paw lifts was counted for 5 min (n). NP, neuropathic pain; EA, electroacupuncture. , , and compared with the NP group.

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