Evidence-Based Complementary and Alternative Medicine

Research Article

Identified the Synergistic Mechanism of Drynariae Rhizoma for Treating Fracture Based on Network Pharmacology

Table 5

Molecular docking of three important protein targets from Drynariae Rhizoma.
Protein targetPDB IDIngredientsDock-IN score
NCOA11NQ7(+)-Catechin7.111
RXRA1DSZ(+)-Catechin4.624
SRC1O4R(+)-Catechin5.908
NCOA11NQ7(2R)-5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one6.694
RXRA1DSZ(2R)-5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one4.605
SRC1O4R(2R)-5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one5.783
NCOA11NQ722-Stigmasten-3-one8.422
RXRA1DSZ22-Stigmasten-3-one5.553
SRC1O4R22-Stigmasten-3-one5.425
NCOA11NQ7Aureusidin7.153
RXRA1DSZAureusidin4.622
SRC1O4RAureusidin5.861
NCOA11NQ7Beta-sitosterol8.34
RXRA1DSZBeta-sitosterol5.587
SRC1O4RBeta-sitosterol5.374
NCOA11NQ7Cycloartenone8.427
RXRA1DSZCycloartenone5.658
SRC1O4RCycloartenone5.693
NCOA11NQ7Cyclolaudenol8.376
RXRA1DSZCyclolaudenol5.534
SRC1O4RCyclolaudenol5.376
NCOA11NQ7Cyclolaudenol acetate8.422
RXRA1DSZCyclolaudenol acetate7.052
SRC1O4RCyclolaudenol acetate6.364
NCOA11NQ7Davallioside A_qt7.904
RXRA1DSZDavallioside A_qt5.779
SRC1O4RDavallioside A_qt5.58
NCOA11NQ7Digallate4.313
RXRA1DSZDigallate3.789
SRC1O4RDigallate3.671
NCOA11NQ7Eriodictyol7.109
RXRA1DSZEriodictyol4.628
SRC1O4REriodictyol5.821
NCOA11NQ7Eriodictyol (flavanone)7.113
RXRA1DSZEriodictyol (flavanone)4.633
SRC1O4REriodictyol (flavanone)5.824
NCOA11NQ7Kaempferol7.125
RXRA1DSZKaempferol4.613
SRC1O4RKaempferol5.929
NCOA11NQ7Luteolin7.089
RXRA1DSZLuteolin4.621
SRC1O4RLuteolin5.847
NCOA11NQ7Naringenin7.12
RXRA1DSZNaringenin6.016
SRC1O4RNaringenin5.883
NCOA11NQ7Stigmasterol8.376
RXRA1DSZStigmasterol5.918
SRC1O4RStigmasterol5.3
NCOA11NQ7Xanthogalenol5.387
RXRA1DSZXanthogalenol7.093
SRC1O4RXanthogalenol7.142