Research Article

Tetrandrine-Induced Autophagy in MDA-MB-231 Triple-Negative Breast Cancer Cell through the Inhibition of PI3K/AKT/mTOR Signaling

Table 1

Comparison of apoptosis rate in different concentrations of tetrandrine group in MDA-MB-231 cells (Mean±SD) (n=3).

GroupNormal cell()Early apoptosis()Late apoptosis()Necrosis()

Control70.65±1.635.00±0.715.35±0.780.25±0.07
Tet (6.4mol/L)49.85±1.7710.45±0.216.80±0.570.55±0.07
Tet (12.8mol/L)25.05±1.9120.75±0.925.70±0.420.25±0.07
Tet (16.1mol/L)13.10±1.5629.95±0.493.45±0.490.35±0.07
Tet (25.7mol/L)8.70±1.1333.90±0.423.40±0.710.25±0.07