Panax Notoginseng Saponins Ameliorate Aβ-Mediated Neurotoxicity in C. elegans through Antioxidant Activities

Figure 3

The effects of PNS on oxidative stress resistance in wild-type strains. (a) PNS enhances survival lifespan after oxidative injury treated by paraquat. Synchronized nematodes were pretreated with PNS or PC for 24h and then exposure to 50 mM paraquat. To obtain the survival curve, the survival time was recorded every 12 hrs. (b) Effect of PNS on ROS levels in nematodes undergoing senescence at day 10. DCF-DA was used as a probe to examine the ROS level; the DCF fluorescence intensity was detected at excitation of 485 nm and emission of 520 nm.

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