Anemoside B4 Protects Rat Kidney from Adenine-Induced Injury by Attenuating Inflammation and Fibrosis and Enhancing Podocin and Nephrin Expression

Figure 6

Fibrosis of kidney and expressions of the factors after the intravenous administration of B4. (a)–(f) Morphology of kidney (200×amplification). (a) normal; (b) model; (c) prednisolone (Predn.); (d) B4 (2.5 mg/kg); (e) B4 (1.25 mg/kg); (f) B4 (0.625 mg/kg); (g) the statistical analysis of the fibrosis in the kidney images by using grayscale scanning. (h)-(j) Protein expression of nephrin and podocin. The data were shown as mean ± SEM from 10 rats in each group. ##, compared with the normal control, P < 0.01. , , compared with model groups, P < 0.05 & P < 0.01. NS means no significance.