Research Article

Safety Concerns of Traditional Chinese Medicine Injections Used in Chinese Children

Table 1

The instructions of ten TCM injections modified by the CFDA since 2006.

TimeTCM InjectionsComponentsInstruments modified by the CFDA

Jun. 2018Shuanghuanglian herbal injecton1. Lonicerae Japonicae Flos
2. Scutellariae Radix
3. Forsythiae Fructus
contraindication in children under four years old and pregnant women
Jun. 2018Qingkailing herbal injection1. Cholic Acid
2. Hyodesoxycholic Acid from Pig Bile
3. Bubali Cornu
4. Baicalin
5. Margaritifera Concha
6. Gardeniae Fructus
7. Isatidis Radix
8. Lonicerae Japonicae Flos
contraindication in newborn, infant and pregnant women
May. 2018Chaihu herbal injectionBupleuri Radixcontraindication in children
Aug. 2016Yinzhihuang herbal injection1. Artemisiae Scopariae Herba
2. Gardeniae Fructus
3. Baicalin
4. Lonicerae Japonicae Flos
contraindication in neonates and infants
Oct. 2015Guanxinning herbal injection1. Salviae Miltiorrhizae Radix et Rhizoma
2. Chuanxiong Rhizoma
contraindication in children and pregnant women
Aug. 2012Honghua herbal injectionCarthami Floscontraindication in children and women during pregnancy or lactation
Mar. 2007Fufang pugongying herbal injection1. Taraxaci Herba
2. Houttuyniae Herba
3. Chrysanthemi Indici Flos
contraindication in children and pregnant women
Mar. 2007Yujin herbal injection1. Houttuyniae Herba
2. Lonicerae Japonicae Flos
Lack of the clinical data for use in children and pregnant women
Nov. 2006Lianbizhi herbal injectionAndrographolide sodium bisulfiteUsage in children, pregnant women, lactating women and old people with caution
Nov. 2006Yuxingcao herbal injectionHouttuyniae Herbacontraindication in children and pregnant women

TCM: traditional Chinese medicine
CFDA: China Food and Drug Administration