Involvement of Interleukin-10 in Analgesia of Electroacupuncture on Incision Pain

Figure 4

Exogenous IL-10 mimicked the analgesic effect of EA. (a) The mechanical allodynia was relieved by IL-10 recombinant protein (1 µg/10 µL) intrathecally injected 1 h before incision (, vs. vehicle). (b) Intrathecal injection of exogenetic IL-10 (1 µg/10 µL) at 1 d after incision alleviated the mechanical allodynia at 0.5 h after injection (, vs. vehicle). (c) The spinal LTP was also blocked by IL-10 recombinant protein (1 µg/10 µL) injected into the spinal subarachnoid space 1 h before TSS (, vs. vehicle). , .

(a)

(b)

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