Research Article
C-Phycocyanin Alleviates Bladder Inflammation and Dysfunction in Cyclophosphamide-Induced Cystitis in a Mouse Model by Inhibiting COX-2 and EP4
Table 1
The inflammatory scores and weight ratio in the three groups.
| | control (n=8) | CYP (n=11) | CPC (n=11) | p(control vs CYP) | p(CYP vs CPC) | p(three groups) |
| hemorrhage | 27.52 ± 8.467 | 81.01 ± 5.606 | 66.46 ± 5.087 | < 0.0001 | 0.069 | < 0.0001 | urothelium damage | 26.48 ± 8.253 | 86.85 ± 9.055 | 92.80 ± 6.054 | < 0.0001 | 0.5908 | < 0.0001 | edema | 14.58 ± 6.379 | 72.47 ± 6.378 | 46.54 ± 5.321 | 0.0002 | 0.007 | 0.0002 | leukocyte infiltration | 18.61 ± 4.227 | 40.70 ± 3.303 | 33.66 ± 5.654 | 0.0003 | 0.0251 | 0.0018 | mastocytes | 2.500 ± 0.1890 | 8.909 ± 1.268 | 5.273 ± 0.4491 | < 0.0001 | 0.0137 | < 0.0001 | Bladder(mg)/body(g) | 0.9456 ± 0.07006 | 2.183 ± 0.1994 | 1.568 ± 0.08215 | < 0.0001 | 0.0015 | < 0.0001 |
| all values were presented in mean ± SEM. |
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All indicators were of significance among the three groups.
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