Arsenic Bioaccessibility of Realgar Influenced by the Other Traditional Chinese Medicines in Niuhuang Jiedu Tablet and the Roles of Gut Microbiota

Table 3

Concentrations of soluble arsenic in simulated gastrointestinal fluid extracts of each group (mean ± SD, n = 6).

Group name	Gastric fluid extract		Intestinal fluid extract		Total extract
	Content (μg/g)	Extraction rate (%)	Content (μg/g)	Extraction rate (%)	Content (μg/g)	Extraction rate (%)
Group R	5411.7 ± 244.7	0.54	2606.0 ± 124.9	0.26	8017.7 ± 267.3	0.80
Group NJT	3513.5 ± 129.9 (↓35.1%)	0.35	1824.7 ± 72.4 (↓30.0%)	0.18	5338.2 ± 123.8 (↓33.4%)	0.53
Group RBC	5339.2 ± 273.1	0.53	2682.0 ± 131.0	0.27	8021.2 ± 376.3	0.80
Group RBS	5540.9 ± 282.7	0.55	2578.4 ± 131.8	0.26	8119.3 ± 384.5	0.81
Group RGF	6123.3 ± 314.5 (↑13.1%)	0.61	2935.7 ± 132.8 (↑12.7%)	0.29	9059.0 ± 321.7 (↑13.0%)	0.91
Group RRR	3283.7 ± 160.3 (↓39.3%)	0.33	1423.0 ± 58.6 (↓45.4%)	0.14	4706.6 ± 191.3 (↓41.3%)	0.47
Group RSR	3076.0 ± 138.0 (↓43.2%)	0.31	1779.1 ± 69.1 (↓31.7%)	0.18	4855.1 ± 183.0 (↓39.4%)	0.49
Group RPR	3737.5 ± 110.8 (↓30.9%)	0.37	1911.2 ± 89.1 (↓26.7%)	0.19	5648.7 ± 157.7 (↓29.5%)	0.57
Group RGR	4904.7 ± 220.9 (↓9.4%)	0.49	2338.0 ± 105.4 (↓10.3%)	0.23	7242.7 ± 256.9 (↓9.7%)	0.72
Group NJT-BC	3599.3 ± 179.0 (↓33.5%)	0.36	1941.0 ± 81.1 (↓25.5%)	0.19	5540.3 ± 227.0 (↓30.9%)	0.55
Group NJT-BS	3728.9 ± 168.0 (↓31.1%)	0.37	1821.2 ± 62.8 (↓30.1%)	0.18	5550.1 ± 137.2 (↓30.8%)	0.56
Group NJT-GF	3324.9 ± 142.7 (↓38.6%)	0.33	1756.7 ± 84.4 (↓32.6%)	0.18	5081.6 ± 190.3 (↓36.6%)	0.51

Compared with group R: , , and versus group NJT.