BRM270 Inhibits the Proliferation of CD44 Positive Pancreatic Ductal Adenocarcinoma Cells via Downregulation of Sonic Hedgehog Signaling

Figure 3

BRM270 inhibits self-renewal capacity of CD44⁺ PDAC cells. (a) Western blotting of stemness genes in lysates treated with and without 50 μg/mL BRM270. (b) Immunocytochemistry staining of stemness genes in CD44⁺ PDAC cells with and without 50 μg/mL BRM270 treatment, scale bar 20 μm. (c) Sphere formation assay of CD44⁺ PDAC cells with and without 50 μg/mL BRM270 treatment, scale bar 100 μm.

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