Luhong Granules Prevent Ventricular Remodelling after Myocardial Infarction by Reducing the Metabolites TMAO and LPS of the Intestinal Flora

Figure 4

Microbial populations in the faeces of rats treated with Luhong granules at 6-week after AMI. Oral administration of Luhong granules (0.75 ml/kg/day) and vancomycin (0.075 g/kg/day) changed the total microbial numbers and altered the abundance of microbial taxa. (a) Venn diagram: the Luhong granule group (684) had the highest species richness, followed by the AMI (587) and sham operation (472) groups, while the vancomycin group (143) had the lowest species richness. (b) Sunburst diagram: at the genus level, Firmicutes and Bacteroides were the two most important genera in the sham operation, AMI, and Luhong granule groups. Proteobacteria, Verrucomicrobia, Firmicutes, and Bacteroides are the main genera in the vancomycin group.

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