Simultaneous Determination of Three Bioactive Constituents from <i>Bletilla striata</i> by UPLC-MS/MS and Application of the Technique to Pharmacokinetic Analyses

<div>Chromatograms of the three analytes and (internal standard, IS) in rat plasma. Blank plasma sample (a); blank rat plasma sample spiked with three analytes (<i>α</i>-isobutylmalic acid, gymnoside I and militarine) and IS (quercetin) (b); rat plasma sample obtained 0.5 h after oral administration and intravenous administration of <i>B. striata</i> extract (c). (1) Puerarin (IS), (2) <i>α</i>-isobutylmalic acid, (3) gymnoside I, (4) militarine.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 2

Figure 2: Simultaneous Determination of Three Bioactive Constituents from <i>Bletilla striata</i> by UPLC-MS/MS and Application of the Technique to Pharmacokinetic Analyses 

Figure 2 | Simultaneous Determination of Three Bioactive Constituents from Bletilla striata by UPLC-MS/MS and Application of the Technique to Pharmacokinetic Analyses 