Effect of Furostanol Saponins from Allium Macrostemon Bunge Bulbs on Platelet Aggregation Rate and PI3K/Akt Pathway in the Rat Model of Coronary Heart Disease

Table 3

FSAMB inhibited PI3K expression and Akt phosphorylation in ADP- (10μmol /L) stimulated platelets. R: resting platelets. Mean ± SD. n =8.P<0.05 and P<0.01 versus model control group.

Group	n	PI3K protein expression ratio (%)	Akt phosphorylation ratio (%)
R	8	29.25±4.85	3.93±0.72
Model control (ADP 10umol/L)	8	100±0.00	100±0.00
FSAMB (168mg/kg)	8	46.68±5.27	36.26±4.60
FSAMB (336mg/kg)	8	39.25±3.60	25.22±3.55
FSAMB (672mg/kg)	8	30.04±5.50	15.34±2.34