Melittin Inhibits Hypoxia-Induced Vasculogenic Mimicry Formation and Epithelial-Mesenchymal Transition through Suppression of HIF-1/Akt Pathway in Liver Cancer

Figure 3

Melittin inhibits CoCl₂-induced EMT in SMMC-7721 cells. (a) Western blot analysis of EMT markers; (b)–(d) the mRNA levels of EMT markers after CoCl₂ treatment with or without melittin were determined by real time RT-PCR. Data are expressed as means ± S.D. (N=3) P<0.05, P<0.01 compared with control group; P<0.05, P<0.01 compared with CoCl₂ group.

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