Baicalein Inhibits Orthotopic Human Non-Small Cell Lung Cancer Xenografts via Src/Id1 Pathway

Figure 2

Baicalein inhibited tumor growth of A549 orthotopic NSCLC xenografts. (a) Gross images of normal lungs and tumor bearing lungs. Nodules can be seen in control group (white arrows). (b) Hematoxylin-eosin (H&E) staining (200X, 400X magnifications) of normal lungs and tumor bearing lungs. Black arrows indicated the tumor cells. (c) Representative micro-CT images of mice in each group showed the lung anatomy and tumor load (yellow arrows) after treatment. (d) Weight of lungs. (e) Changes of mice weight in each group over time. Data was shown as mean ± SEM, P<0.05; P<0.01.

(a)

(b)

(c)

(d)

(e)