Effectiveness of Aqueous Extract of Marine Baitworm Marphysa moribidii Idris, Hutchings and Arshad, 2014 (Annelida, Polychaeta), on Acute Wound Healing Using Sprague Dawley Rats
Table 1
Rat’s behaviour in an individual cage for 30 min of observation in the morning throughout 14 days of wound healing using several treatments.
Treatment
Activity/day
0
3
7
11
14
NO
Wound licking/scratching
+
+
+
−
−
Sleeping/resting
+
+
+
−
−
Cage exploration (walking/climbing)
−
−
+
+
+
PCG
Wound licking/scratching
+
+
−
−
−
Sleeping/resting
+
+
−
−
−
Cage exploration (walking/climbing)
−
−
+
+
+
PCA
Wound licking/scratching
+
+
−
−
−
Sleeping/resting
+
+
−
−
−
Cage exploration (walking/climbing)
−
−
+
+
+
PE 0.1%
Wound licking/scratching
+
+
−
−
−
Sleeping/resting
+
+
−
−
−
Cage exploration (walking/climbing)
−
−
+
+
+
PE 0.5%
Wound licking/scratching
+
+
−
−
−
Sleeping/resting
+
+
−
−
−
Cage exploration (walking/climbing)
−
−
+
+
+
PE 1.0%
Wound licking/scratching
+
+
−
−
−
Sleeping/resting
+
+
−
−
−
Cage exploration (walking/climbing)
−
−
+
+
+
NC
Wound licking/scratching
+
+
+
−
−
Sleeping/resting
+
+
−
−
−
Cage exploration (walking/climbing)
−
−
+
+
+
Rats’ wounds were treated with NO = no treatment (negative control), PCG = 15% positive control gamat, PCA = 0.1% positive control acriflavine, PE 0.1% = 0.1% polychaete extract, PE 0.5% = 0.5% polychaete extract, PE 1.0% = 1.0% polychaete extract prepared in cetomacrogol ointment, and NC = cetomacrogol ointment (negative control). n = 5. − = no activity; + = presence of activity.
