In Vivo Diuretic Activity of Hydromethanolic Extract and Solvent Fractions of the Root Bark of Clerodendrum myricoides Hochst. (Lamiaceae)

Table 2

Diuretic index of solvent fractions of the root bark of Clerodendrum myricoides at 6th hr and 24th hr.

Dose (mg/kg)	Posttreatment (at 6th hr)			Posttreatment (at 24th hr)
	Urinary excretion	Diuretic action	Diuretic index	Urinary excretion	Diuretic action	Diuretic index
AF400	37.11	0.86	0.44	112.56	1.07	0.59
AF200	58.74	1.37	0.70	137.09	1.30	0.71
AF100	47.10	1.10	0.56	130.5	1.24	0.68
EAF400	95	1.59	0.94	192.33	1.73	1.01
EAF200	74.16	1.24	0.73	165.83	1.49	0.87
EAF100	76.87	1.29	0.76	151.5	1.36	0.79
CF400	84.67	1.42	0.84	175.16	1.57	0.91
CF200	40.91	0.68	0.40	172.13	1.55	0.90
CF100	63.16	1.06	0.63	135.33	1.21	0.70
F10	100.16	1.68	1	190.51	1.71	1
DW	42.85	—	—	105	—	—
2%TDW	59.46	—	—	111	—	—

AF, aqueous fraction; F10, furosemide 10 mg/kg; DW, distilled water; EAF, ethyl acetate fraction; CF, chloroform fraction; and 2%TDW, 2% Tween 80 in distilled water.