Evaluation of Methanol-Dichloromethane Extract of Stemonocoleus micranthus Harms (Fabaceae) Stem Bark for Anti-Inflammatory and Immunomodulatory Activities

Table 3

Effect of MDESm on cotton pellet-induced granuloma in rats.

Treatment	Dose (mg/kg)	Mean weight (mg)	% reduction
Control (dist. water)	2 (ml/kg)	0.28 ± 0.02	—
Ibuprofen	100	0.19 ± 0.032	32.14
MDESm	100	0.17 ± 0.016	39.28
MDESm	200	0.23 ± 0.029	17.85
MDESm	400	0.23 ± 0.012	17.85

Mean ± SEM, n = 5; compared to control (one-way ANOVA; Dunnett’s post hoc tests). MDESm = methanol-dichloromethane extract of Stemonocoleus micranthus.