Evaluation of Methanol-Dichloromethane Extract of Stemonocoleus micranthus Harms (Fabaceae) Stem Bark for Anti-Inflammatory and Immunomodulatory Activities
Table 7
Effect of MDESm on haematological parameters in mice.
Treatment
Dose (mg/kg)
WBC (cells/μL)
Hb (g/dL)
Platelets (cells/μL)
Neutrophil (cells/μL)
Lymphocytes (cells/μL)
Control (dist. water)
—
9120 ± 1563
13.38 ± 0.31
222000 ± 48104
22.4 ± 3.74
77.6 ± 3.74
Levamisole
50
15880 ± 3172
13.46 ± 0.44
388000 ± 77549
21.0 ± 3.79
79.0 ± 3.79
MDESm
100
10575 ± 1003
11.90 ± 0.40
255000 ± 71821
18.7 ± 3.42
81.3 ± 3.42
MDESm
200
7980 ± 1285
13.90 ± 0.85
200000 ± 35777
23.6 ± 3.50
76.8 ± 3.73
MDESm
400
9925 ± 726
13.49 ± 0.68
217500 ± 51700
22.2 ± 3.81
77.5 ± 3.81
Mean ± SEM, n = 5; compared to control (one-way ANOVA; Dunnett’s post hoc test). MDESm = methanol-dichloromethane extract of Stemonocoleus micranthus.
