Evaluation of Methanol-Dichloromethane Extract of Stemonocoleus micranthus Harms (Fabaceae) Stem Bark for Anti-Inflammatory and Immunomodulatory Activities

Table 8

Effect of MDESm on biochemical parameters in rats.

Treatment	Dose (mg/kg)	AST (IU/L)	ALT (IU/L)	ALP (IU/L)
Control (dist. water)	−50	48.2 ± 5.60	22.7 ± 3.22	40.7 ± 7.98
Levamisole		55.4 ± 9.21	24.2 ± 3.18	46.2 ± 8.64
MDESm	100	49.3 ± 13.33	19.3 ± 2.02	21.6 ± 13.90
MDESm	200	45.6 ± 3.04	15.8 ± 2.57	15.8 ± 9.89
MDESm	400	59.0 ± 11.32	13.0 ± 5.70	37.6 ± 10.00

Mean = ± SEM, n = 5; compared to control (one-way ANOVA; Dunnett’s post hoc test). MDESm = methanol-dichloromethane extract of Stemonocoleus micranthus; ALT = alanine transaminase; ALP = alkaline phosphatase; AST = aspartate transaminase.