Research Article
Efficacy and Safety of Traditional Chinese Medicine in Idiopathic Pulmonary Fibrosis: A Meta-Analysis
Table 4
Subgroup analysis of the efficacy of TCM on idiopathic pulmonary fibrosis according to comparison models
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| Measurements | TCM vs. WM | TCM + WM vs. WM or TCM vs. Placebo | SMD (95% CI) | | I2 (%) | SMD (95% CI) | | I2 (%) |
| PO2 | 0.35 (−0.03, 0.73) | 0.072 | 68.7 | 0.93 (0.66, 1.20) | <0.001 | 75.9 | FEV1/FVC | — | — | — | 0.98 (0.52, 1.44) | <0.001 | 78.7 | FVC% | 0.52 (0.23, 0.82) | 0.001 | 38.5 | 0.62 (0.38, 0.87) | <0.001 | 62.8 | FEV1% | 0.67 (0.19, 1.16) | 0.007 | 63.6 | 0.53 (0.37, 0.70) | <0.001 | 0 | TLC% | 0.19 (0.02, 0.36) | 0.028 | 0 | 0.37 (0.18, 0.56) | <0.001 | 24.4 | DLCO% | 0.33 (0.10, 0.57) | 0.006 | 53.5 | 0.46 (0.33, 0.60) | <0.001 | 16.8 | DLCO | 1.19 (1.01, 1.37) | <0.001 | 45.6 | — | — | — | VC% | 0.39 (0.00, 0.79) | 0.050 | 50.6 | 0.33 (0.14, 0.53) | 0.001 | 26.5 | 6MWD | 0.58 (0.39, 0.78) | <0.001 | 40.0 | 0.83 (0.63, 1.04) | <0.001 | 0 | SGRQ | — | — | — | −0.38 (−0.65, −0.10) | 0.008 | 63.5 |
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Only the subgroups involving at least 3 studies were analyzed; TCM: traditional Chinese medicine; WM: western medicine. |