Research Article

Efficacy and Safety of Traditional Chinese Medicine in Idiopathic Pulmonary Fibrosis: A Meta-Analysis

Table 4

Subgroup analysis of the efficacy of TCM on idiopathic pulmonary fibrosis according to comparison models.

MeasurementsTCM vs. WMTCM + WM vs. WM or TCM vs. Placebo
SMD (95% CI)I2 (%)SMD (95% CI)I2 (%)

PO20.35 (−0.03, 0.73)0.07268.70.93 (0.66, 1.20)<0.00175.9
FEV1/FVC0.98 (0.52, 1.44)<0.00178.7
FVC%0.52 (0.23, 0.82)0.00138.50.62 (0.38, 0.87)<0.00162.8
FEV1%0.67 (0.19, 1.16)0.00763.60.53 (0.37, 0.70)<0.0010
TLC%0.19 (0.02, 0.36)0.02800.37 (0.18, 0.56)<0.00124.4
DLCO%0.33 (0.10, 0.57)0.00653.50.46 (0.33, 0.60)<0.00116.8
DLCO1.19 (1.01, 1.37)<0.00145.6
VC%0.39 (0.00, 0.79)0.05050.60.33 (0.14, 0.53)0.00126.5
6MWD0.58 (0.39, 0.78)<0.00140.00.83 (0.63, 1.04)<0.0010
SGRQ−0.38 (−0.65, −0.10)0.00863.5

Only the subgroups involving at least 3 studies were analyzed; TCM: traditional Chinese medicine; WM: western medicine.