Research Article

Antiproliferative Effects of Alkaloids from the Bulbs of Crinum abyscinicum Hochst. ExA. Rich

Table 1

Antiproliferative activity of the bulb extract of Crinum abyscinicum, 6-hydroxycrinamine, and lycorine against A2780 and MV4-11 cell lines.

Sample nameGI50 (μg/ml ± SD)
A2780MV4-11

Bulb extract20.8 ± 0.48.3 ± 0.3
6-Hydroxycrinamine (1)2.9 ± 0.85.3 ± 0.5
Lycorine (2)2.8 ± 0.13.4 ± 0.3
Palbociclib0.03 ± 0.0080.06 ± 0.002