Research Article

Electroacupuncture and Moxibustion Regulate Hippocampus Glia and Mitochondria Activation in DSS-Induced Colitis Mice

Figure 4

EA and moxibustion modulate microglia activation. Labeling (a) and analysis (b–d) of microglia in the hippocampus CA1 (b), CA3 (c), and DG (d) regions of UC mice. Green, Iba-1 (a marker of activated microglia); blue, DAPI nuclear staining (n = 5/group). Scale bar, 50 μm. White arrow highlights the state change of microglia, from resting in control mice (faint Iba-1 staining) to activation in UC mice (DSS-induced; strong Iba-1 staining) and also improvement after EA and moxibustion treatment. Iba1, ionized calcium binding adapter molecule 1.
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