Effect of Rosa laevigata on PM10-Induced Inflammatory Response of Human Lung Epithelial Cells

Figure 4

Inhibitory effects of RL on MAPK/NF-κB pathways in PM10-treated A549 cells. RL (125 and 250 μg/mL) was pretreated 1 h prior to PM10-induced inflammation in A549 cells and incubated for 24 h with PM10 (100 μg/mL). (a)–(d) Inhibitory effects of RL on protein expression of p38, ERK 1/2, JNK, and NF-κB p65 in PM10-treated A549 cells. Ratio of each protein was measured by ImageJ. Statistical significance was analyzed by unpaired t-test (one-tailed). Values are means ± SEM. ; compared to the control group. compared to only PM10-treated group.

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