Potential Effects of Antioxidant and Serum Cholesterol-Lowering Effects of Gynura bicolor Water Extracts in Syrian Hamster

Table 2

Effects of the GBWE on the TBARS and GSH levels in hamsters fed an HFD for 12 weeks.

Group	TBARS	GSH	GSSG	GSH/GSSG
	nmol/mg protein			%
ND	0.20 ± 0.02^ab	50.1 ± 1.4^a	1.2 ± 0.2^b	40.6 ± 2.0^a
HFD	0.28 ± 0.08^a	43.6 ± 1.6^b	1.6 ± 0.3^a	26.7 ± 1.6^b
Probucol	0.21 ± 0.05^ab	48.2 ± 2.4^a	1.2 ± 0.1^b	39.3 ± 3.0^a
GBWE-L	0.16 ± 0.03^b	49.4 ± 2.2^a	1.1 ± 0.1^b	44.1 ± 2.7^a
GBWE-H	0.19 ± 0.04^b	56.7 ± 2.8^a	1.0 ± 0.1^b	56.2 ± 3.1^a

TBARSs, thiobarbituric acid reactive substances; GSH, glutathione; GSSG, oxidative glutathione; GBWE, G. bicolor water extract; HFD, high-fat diet; GBWE-L, 0.4 g/kg body weight GBWE; GBWE-H, 0.8 g/kg body weight GBWE. The values are presented as the means ± standard deviations from four to five repeats. Groups with different letters (a, b, and c) in the same column are significantly different, as demonstrated by Duncan’s test ().