Potential Effects of Antioxidant and Serum Cholesterol-Lowering Effects of Gynura bicolor Water Extracts in Syrian Hamster

Table 3

Effects of the GBWE on the blood lipid and lipoprotein profiles of hamsters fed an HFD for 12 weeks.

Group	TGs	TC	LDL-C	HDL-C
	mg/dL
ND	27.4 ± 5.1	124 ± 10^c	36.6 ± 5.9^c	98±8^c
HFD	32.6 ± 4.8	226 ± 16^a	73.8 ± 9.6^a	165 ± 15^b
Probucol	30.0 ± 6.5	165 ± 13^b	68.3 ± 4.2^ab	164 ± 12^b
GBWE-L	28.2 ± 8.3	171 ± 15^b	68.3 ± 10.3^ab	162 ± 12^b
GBWE-H	28.8 ± 7.1	159 ± 11^b	56.3 ± 5.3^b	186 ± 10^a

TC, total cholesterol; TG, total triglyceride; LDL-C, low-density lipoprotein-cholesterol; HDL-C, high-density lipoprotein-cholesterol; GBWE, G. bicolor water extract; HFD, high-fat diet; GBWE-L, 0.4 g/kg body weight GBWE; GBWE-H, 0.8 g/kg body weight GBWE. The values are presented as the means ± standard deviations from four to five repeats. Groups with different letters (a, b, and c) in the same column are significantly different, as demonstrated by Duncan’s test ().