A Multicenter Randomized Controlled Pilot Trial Testing the Efficacy and Safety of Pterygopalatine Fossa Puncture Using One Acupuncture Needle for Moderate-to-Severe Persistent Allergic Rhinitis

Table 4

Effect of treatment on Rhinitis Quality of Life Questionnaire score.

	Intervention	Verum acupuncture	value
	ITT	ITT
Activities
Baseline	12.07 ± 3.34	11.53 ± 5.67	0.671
1 week	9.61 ± 3.84	8.93 ± 5.34	0.528
2 weeks	8.72 ± 4.23	7.73 ± 4.73	0.383
3 weeks	7.32 ± 4.21	6.93 ± 4.47	0.672
4 weeks	7.81 ± 4.35	6.78 ± 4.47	0.489
Sleep
Baseline	6.83 ± 4.37	7.82 ± 4.63	0.272
1 week	4.93 ± 2.98	6.28 ± 4.63	0.132
2 weeks	3.93 ± 2.97	5.22 ± 4.21	0.123
3 weeks	3.34 ± 2.87	4.98 ± 3.57	0.033∗
4 weeks	3.15 ± 3.36	4.43 ± 4.01	0.127
Nonnasal/eye
Baseline	15.87 ± 6.73	16.47 ± 7.81	0.672
1 week	13.67 ± 5.54	13.78 ± 7.37	0.924
2 weeks	11.37 ± 6.67	12.87 ± 7.47	0.362
3 weeks	8.81 ± 6.37	10.67 ± 6.34	0.223
4 weeks	7.97 ± 6.32	9.53 ± 6.16	0.283
Practical problems
Baseline	13.23 ± 3.45	12.23 ± 4.27	0.242
1 week	10.67 ± 2.82	9.98 ± 3.34	0.127
2 weeks	8.67 ± 3.32	8.67 ± 3.43	0.947
3 weeks	8.27 ± 3.34	7.89 ± 3.61	0.463
4 weeks	6.87 ± 3.19	7.85 ± 3.25	0.329
Nasal problems
Baseline	12.57 ± 2.27	12.38 ± 3.47	0.747
1 week	9.89 ± 2.87	9.36 ± 3.73	0.531
2 weeks	8.56 ± 3.12	9.21 ± 3.63	0.446
3 weeks	7.22 ± 3.03	8.47 ± 3.69	0.113
4 weeks	6.78 ± 3.46	7.92 ± 3.60	0.121
Eye symptoms
Baseline	9.58 ± 6.59	7.86 ± 4.51	0.029
1 week	5.78 ± 4.67	4.27 ± 3.58	0.084
2 weeks	4.21 ± 3.21	3.78 ± 3.37	0.534
3 weeks	3.39 ± 2.87	3.17 ± 2.91	0.887
4 weeks	2.98 ± 1.87	3.03 ± 2.88	0.936
Emotional function
Baseline	9.83 ± 5.37	7.87 ± 4.98	0.078
1 week	6.47 ± 3.96	6.13 ± 4.27	0.728
2 weeks	4.47 ± 3.43	5.31 ± 4.75	0.315
3 weeks	3.57 ± 3.21	4.25 ± 3.97	0.457
4 weeks	3.25 ± 3.36	3.38 ± 3.91	0.487

. ITT, intention-to-treat.