In Vitro and Randomized, Double‐Blind, Placebo‐Controlled Trial to Determine the Efficacy and Safety of Nine Antiacne Medicinal Plants

Table 3

Acne severity index (ASI) was evaluated in a double-blind, randomized, and controlled efficacy study with 41 acne patients, aged 18–24 years, who were asked to apply antiacne herbal cream (AHC) (n = 27) two to three times daily for six weeks.

ASI (acne severity index) of AHC group
Patient no.	Baseline	Week 2	Week 5	Week 6
	ASI	ASI	ASI	ASI
1	16.25	7.50	1.75	2.25
2	15.00	7.50	2.50	1.00
3	18.75	9.50	3.25	3.00
4	14.25	5.00	0.00	0.00
5	13.00	5.00	0.00	0.00
6	8.75	1.25	0.50	0.25
7	12.75	3.50	0.25	0.00
8	21.25	10.00	3.75	3.25
9	14.00	5.25	2.25	1.00
10	21.50	10.25	2.00	1.00
11	26.00	13.00	4.50	2.00
12	21.75	9.25	5.00	2.25
13	30.50	16.25	8.25	5.50
14	11.50	4.75	0.00	0.00
15	14.25	6.50	3.25	1.50
16	12.25	7.50	1.00	0.25
17	12.00	5.25	0.00	0.00
18	19.50	9.00	2.00	1.00
19	28.75	11.25	4.00	2.00
20	17.50	5.75	2.00	1.00
21	28.50	15.50	4.75	3.75
22	20.25	9.25	4.50	2.00
23	18.75	10.00	4.75	2.25
24	17.50	7.25	2.00	1.00
25	21.00	10.50	5.00	4.00
26	13.25	4.25	0.00	0.00
27	19.00	9.75	4.25	2.00
Average	18.06	8.14	2.65	1.56
STDEV	5.65	3.5098	2.129	1.4321
St. err.	1.23	0.77	0.46	0.31
	t	19.37	14.19	5.70
		<0.05	<0.05	<0.05