Review Article

Effectiveness and Safety of Acupuncture Moxibustion Therapy Used in Breast Cancer-Related Lymphedema: A Systematic Review and Meta-Analysis

Table 1

Characteristics of included studies.

Study IDNumber (T/C)Age, years (T/C)InterventionsOutcomesQuality of the evidence (GRADE)
Control groupTreatment groupFollow-up visitDuration

Zhao, 201936/3643.25 ± 9.29/46.25 ± 9.72PhysiotherapyPhysiotherapy + electroacupuncture + auricular acupuncture2 months1, 2, 4㊉ ㊉ ㊉Moderate
Zhan, 201730/3030–70, mean: 57.84 ± 4.48Functional trainingFunctional training + manual acupuncture28 days1㊉ ㊉ ㊉Moderate
Zhao, 201246/4647.2/46.4PhysiotherapyMoxibustion4 weeks9 weeks1㊉ ㊉ ㊉Moderate
Yang, 201722/2358.25 ± 6.19/59.42 ± 7.02PhysiotherapyMoxibustion4 months4 weeks3, 4㊉ ㊉ ㊉Moderate
Liu, 201940/4046.37 ± 14.53/49.32 ± 13.22Western medicineMoxibustion28 days1, 3㊉ ㊉ ㊉Moderate
Liu, 201930/3055 ± 11/55 ± 10PhysiotherapyMoxibustion42 days1, 2㊉ ㊉ ㊉Moderate
Huang, 201431/3130–73, mean: 45.5Functional training + Western medicineFunctional training + moxibustion6 weeks1㊉ ㊉ ㊉Moderate
Jiang, 201530/3018–70PhysiotherapyPhysiotherapy + moxibustion8 weeks2㊉ ㊉ ㊉Moderate
Yao, 201615/1556.2 ± 5.82/55.8 ± 5.02PhysiotherapyMoxibustion30 days2, 4㊉ ㊉ ㊉ ㊉High
Bao, 201840/4265 (54, 71)/58 (49, 70)PhysiotherapyManual acupuncture3 months6 weeks2, 4㊉ ㊉ ㊉ ㊉High
Chen, 201830/3055 ± 11.8/54.93 ± 9.5PhysiotherapyAcupressure + Chinese medicine packets28 days1㊉ ㊉ ㊉Moderate
Zhang, 201650/2559.90 ± 7.02/56.96 ± 5.33Functional trainingFunctional training + bloodletting puncture and cupping50 days1, 3, 4㊉ ㊉ ㊉Moderate

Outcomes: (1) total effective rate; (2) circumference difference; (3) KPS score; and (4) adverse effects.