Ethyl Acetate Fraction from Hedyotis diffusa plus Scutellaria barbata Suppresses Migration of Bone-Metastatic Breast Cancer Cells via OPN-FAK/ERK/NF-κB Axis

Figure 2

Effect of EA11 on wound healing of MCF-7-BOM cells. (a) A scratch was generated with a pipette tip, and cells were grown with or without EA11 treatment at concentrations of vehicle, 25, and 50 μg/ml. Images were taken at 0, 24 h, and 48 h under a phase-contrast microscope. (b) Cells were grown by treatment of EA11 at concentrations of vehicle, 25, and 50 μg/ml. The mobility in 3 random fields of vehicle, 24, and 48 H treated with vehicle, 25, and 50 μg/ml EA11. Data are means ± SD. n = 3. , vs. vehicle.

(a)

(b)