Sini-San Regulates the NO-cGMP-PKG Pathway in the Spinal Dorsal Horn in a Modified Rat Model of Functional Dyspepsia

Figure 1

Experimental procedures and time line: 10-day-old rats were treated with 0.1% IA for 6 days. Rats were then normally housed to 7-week-old and performed with tail-clamping for 7 days. After that, 8-week-old rats received normal saline or SNS treatments for 7 days. Then, rats were housed to 9-week-old and received implantation of intragastric balloon and electrodes. At the age of 10 weeks, all rats were performed with behavioral testing before sampling and tissue preparation.