Antidiabetic Effects of Arginyl-Fructosyl-Glucose, a Nonsaponin Fraction from Ginseng Processing in Streptozotocin-Induced Type 2 Diabetic Mice through Regulating the PI3K/AKT/GSK-3β and Bcl-2/Bax Signaling Pathways

Table 2

Effects of AFG on body weight of DM mice (, n = 12).

Group	Dosage (mg/kg)	Before administration	After administration
			4 weeks	Weight gain (g)	Liver index (mg/g)	Spleen index (mg/g)
Normal	—	38.75 ± 3.29	40.35 ± 2.92	1.60	47.10 ± 2.87	3.43 ± 0.90
STZ	—	38.94 ± 4.51	35.68 ± 2.49^##	−3.26	63.90 ± 4.78^##	5.37 ± 0.73^#
AFG	20	38.91 ± 2.77	38.94 ± 2.86	0.03	50.21 ± 4.35	4.64 ± 0.84
	40	38.09 ± 3.63	38.31 ± 3.94	0.22	48.93 ± 3.94	4.41 ± 0.65
	80	38.81 ± 3.49	39.51 ± 3.18	0.70	50.74 ± 5.38	3.66 ± 0.57

, , as equated with the normal group; , , as equated with the STZ group. The same as follows.