Identification of Active Compounds of Mahuang Fuzi Xixin Decoction and Their Mechanisms of Action by LC-MS/MS and Network Pharmacology

Table 2

ADME profile of the compounds from MFXD.

Compounds	Caco-2	HIA	F20	F30
Gallic acid	−5.767	0.431	0.673	0.616
Cathine	−4.783	0.877	0.851	0.869
Ephedrine	−4.956	0.902	0.853	0.879
Higenamine	−5.293	0.538	0.226	0.386
Pseudoephedrine	−4.956	0.902	0.853	0.879
Methylephedrine	−4.477	0.809	0.701	0.707
Vicenin-2	−6.624	0.226	0.447	0.253
Catechin	−6.495	0.400	0.488	0.404
Kaempferitrin	−6.364	0.399	0.584	0.325
Vitexin	−6.317	0.263	0.494	0.287
p-Coumaric acid	−4.892	0.745	0.699	0.536
Quercitrin	−6.469	0.155	0.515	0.242
Naringenin chalcone	−5.198	0.472	0.596	0.519
Umbelliferone	−4.601	0.797	0.534	0.441
Benzoylmesaconine	−6.087	0.301	0.332	0.41
Germacrone	−4.378	0.768	0.661	0.625
Coumarin	−4.142	0.848	0.288	0.257
Ferulic acid	−4.943	0.635	0.680	0.509
Hypaconitine	−5.513	0.343	0.265	0.350
Deoxyaconitine	−5.469	0.349	0.261	0.355
Atractylenolide II	−4.35	0.866	0.564	0.549
Nardosinone	−4.353	0.826	0.633	0.585
β-Asarone	−4.379	0.763	0.722	0.681
Linolenic acid	−4.729	0.805	0.568	0.396