Long-Term Traditional Chinese Medicine Combined with NA Antiviral Therapy on Cirrhosis Incidence in Chronic Hepatitis B Patients in the Real-World Setting: A Retrospective Study

Table 2

Incidence of cirrhosis for CHB patients with different baseline characteristics.

Characteristics	Cirrhosis (n = 53)	Noncirrhosis (n = 468)	value
Age (years)			0.965
<40	32 (10.1)	284 (89.9)
≥40	21 (10.2)	184 (89.8.9)
Gender (n, %)			0.021
Male	42 (12.4)	296 (65.8)
Female	11 (6.0)	172 (94.0)
Duration of illness (n, %)			0.158
0∼5	5 (3.8)	127 (96.2)
5∼10	9 (8.7)	94 (91.3)
10∼15	14 (11.6)	107 (88.4)
15∼	25 (15.2)	140 (84.8)
Smoking history (n, %)			0.419
Yes	8 (12.6)	53 (10.8)
No	45 (87.4)	415 (89.2)
Drinking history (n, %)			0.032
Yes	14 (16.7)	70 (83.3)
No	39 (82.8)	398 (91.1)
Family history of CHB-related diseases (n, %)			0.016
Yes	27 (13.7)	170 (86.3)
No	26 (8.0)	298 (92.0)
HBeAg			0.027
Positive	39 (12.5)	270 (87.5)
Negative	14 (6.6)	198 (93.4)
HBV DNA level (copies/mL)			0.022
10^3∼10^4	3 (4.1)	71 (95.9)
10^4∼10^5	4 (3.3)	56 (96.7)
10^5∼10^6	6 (7.5)	74 (92.5)
10^6∼10^7	11 (11.7)	83 (88.3)
10^7	29 (14.6)	184 (85.4)
ALT (IU/ml ULN)			0.473
1∼2	8 (7.8)	94 (92.2)
2∼3	26 (9.8)	240 (90.2)
3∼	19 (12.4)	134 (87.6)