Research Article

Network Pharmacology Strategy to Investigate the Pharmacological Mechanism of HuangQiXiXin Decoction on Cough Variant Asthma and Evidence-Based Medicine Approach Validation

Table 1

Basic information on the active compounds in HQXXD.

MedicineActive compoundCompound IDOB (%)DL

RAMairinMOL00021155.380.78
RAJaranolMOL00023950.830.29
RAHederageninMOL00029636.910.75
RA(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-[(2R,5S)-5-propan-2-yloctan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-olMOL00003336.230.78
RAIsorhamnetinMOL00035449.60.31
RA3,9-Di-O-methylnissolinMOL00037153.740.48
RA5′-Hydroxyiso-muronulatol-2′,5′-di-O-glucosideMOL00037441.720.69
RA7-O-MethylisomucronulatolMOL00037874.690.3
RA9,10-Dimethoxypterocarpan-3-O-β-D-glucosideMOL00037936.740.92
RA(6aR,11aR)-9,10-Dimethoxy-6a,11a-dihydro-6H-benzofurano[s3,2-c]chromen-3-olMOL00038064.260.42
RABifendateMOL00038731.10.67
RAFormononetinMOL00039269.670.21
RAIsoflavanoneMOL000398109.990.3
RACalycosinMOL00041747.750.24
RA
HRA
KaempferolMOL00042241.880.24
RAFAMOL00043368.960.71
RA(3R)-3-(2-Hydroxy-3,4-dimethoxyphenyl)chroman-7-olMOL00043867.670.26
RAIsomucronulatol-7,2′-di-O-glucosioleMOL00043949.280.62
RA1,7-Dihydroxy-3,9-dimethoxypterocarpeneMOL00044239.050.48
RA
HS
QuercetinMOL00009846.430.28
HRA4,9-Dimethoxy-1-vinyl-b-carbolineMOL01214065.30.19
HRACaribineMOL01214137.060.83
HRACryptopinMOL00146078.740.72
HRASesaminMOL00155856.550.83
HRA[(1S)-3-[(E)-But-2-enyl]-2-methyl-4-oxo-1-cyclopent-2-enyl](1R,3R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylateMOL00250162.520.31
HRA(3S)-7-Hydroxy-3-(2,3,4-trimethoxyphenyl) chroman-4-oneMOL00296248.230.33
HRAZINC05223929MOL00984931.570.83
HSSchizonepetoside BMOL01184931.020.28
HSSchkuhrin IMOL01185654.450.52
HSDiosmetinMOL00288131.140.27
HS
RS
SitosterolMOL00035936.910.75
HS5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-oneMOL00510047.740.27
HSLuteolinMOL00000636.160.25
HS
RS
Beta-sitosterolMOL00035836.910.75
HSStigmasterolMOL00044943.830.76
HSSupraeneMOL00150633.550.42
HSCampest-5-en-3beta-olMOL00504337.580.71
RS(2R,3R)-3-(4-Hydroxy-3-methoxy-phenyl)-5-methoxy-2-methylol-2,3-dihydropyrano [5,6-h][1,4]benzodioxin-9-oneMOL00001168.830.66
RS11-Hydroxy-sec-o-beta-d-glucosylhamaudol_qtMOL01173050.240.27
RSAnomalinMOL01173259.650.66
RSDivaricatacidMOL011737870.32
RSDivaricatolMOL01174031.650.38
RSAmmidinMOL00194134.550.22
RSLedebouriellolMOL01174732.050.51
RSPhelloptorinMOL01174943.390.28
RS5-O-MethylvisamminolMOL01175337.990.25
RSPhellopterinMOL00264440.190.28
RSWogoninMOL00017330.680.23
RSMandenolMOL001494420.19
RSIsoimperatorinMOL00194245.460.23
RSPrangenidinMOL00358836.310.22
RSMethyl icosa-11,14-dienoateMOL00751439.670.23
RSDecursinMOL01307739.270.38