Review Article
Meta-Analysis Based on Clinical RCTs: The Effect of Molecular Epimerism on the Safety of Glycyrrhizic Acid
Table 2
The presentation and number of ADRs in the MI and CG groups.
| ADR presentation | MI group | CG group | Number of ADRs | Proportion (%) | Number of ADRs | Proportion (%) |
| Lower limb edema | 3 | 10.71 | 23 | 20.18 | Dizziness, headache | 6 | 21.43 | 21 | 18.42 | Increased blood pressure | 2 | 7.14 | 20 | 17.54 | Palpitation | 5 | 17.86 | 13 | 11.40 | Facial edema | 3 | 10.71 | 16 | 14.04 | Gastrointestinal reaction | 5 | 17.86 | 8 | 7.02 | Decreased muscle strength | 2 | 7.14 | 7 | 6.14 | Hypokalemia | 1 | 3.57 | 3 | 2.63 | Hyperkalemia | 0 | 0.00 | 0 | 0.00 | Urine occult blood | 0 | 0.00 | 1 | 0.88 | Facial flushing | 0 | 0.00 | 1 | 0.88 | Skin rash | 1 | 3.57 | 1 | 0.88 | Total | 28 | 100.00 | 114 | 100.00 |
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