Research Article

Complementary and Alternative Medicines for the Treatment of Hepatitis C: Perspectives of Users and CAM Practitioners

Table 2

Perception of interviewed patients and providers regarding prevailing side effects and complications from allopathic medicines.

Prior medicinePatient (n = 284)Practitioner (n = 133)
SOF (n = 46)PEG-INF (n = 122)Silymarin (n = 47)Other (n = 69)SOF (n = 24)PEG-INF (n = 100)Silymarin (n = 2)Other (n = 7)

Side effects
 Nausea/Vomiting13 (28.3)43 (35.2)20 (42.6)28 (40.6)5 (20.8)34 (34.0)0 (0.0)3 (42.8)
 Skin allergy4 (8.7)24 (19.7)2 (4.3)11 (15.9)0 (0.0)2 (2.0)1 (50.0)1 (14.3)
 Persistent fever7 (15.2)13 (10.6)7 (14.9)10 (14.5)7 (29.2)11 (11.0)1 (50.0)0 (0.0)
 GIT disturbance1 (2.2)6 (4.9)0 (0.0)3 (4.3)2 (8.3)8 (8.0)0 (0.0)0 (0.0)
 Multiple21 (45.6)36 (29.5)18 (38.3)17 (24.6)10 (41.7)45 (45.0)0 (0.0)3 (42.8)

Complications
 Anemia9 (19.6)43 (35.2)11 (23.4)13 (18.8)7 (29.2)30 (30.0)0 (0.0)3 (42.8)
 Ascites2 (4.3)7 (5.7)1 (2.1)3 (4.3)10 (41.7)39 (39.0)1 (50.0)1 (14.3)
 Constipation11 (23.9)21 (17.2)17 (36.2)25 (36.2)2 (8.3)15 (15.0)0 (0.0)2 (28.6)
 Depression10 (21.7)14 (11.5)4 (8.5)5 (7.2)3 (12.5)9 (9.0)1 (50.0)0 (0.0)
 Kidney problem2 (4.4)5 (4.1)5 (10.6)1 (1.4)1 (4.2)6 (6.0)0 (0.0)0 (0.0)
 Multiple12 (26.1)32 (26.2)9 (19.1)22 (31.9)1 (4.2)1 (1.0)0 (0.0)1 (14.3)

Abbreviations: SOF = sofosbuvir, PEG-INF = pegylated-interferon, GIT = gastrointestinal tract, and multiple = more than one symptom.