Traditional Chinese Medicine Treatment Associated with Female Infertility in Taiwan: A Population-Based Case-Control Study

Table 4

Unadjusted and adjusted odd ratios of successful pregnancy for individual commonly used fertility drugs.

Fertility drugs	N	%	Unadjusted OR (95% CI)	Adjusted OR (95% CI)
TCM prescription
Jia-Wei-Xiao-Yao-San	253	4.82	3.47 (2.58, 4.67)	3.17 (2.35, 4.28)
Wen-Jing-Tang	213	4.05	3.15 (2.30, 4.32)	2.83 (2.06, 3.90)
Dang-Gui-Sha-Yao-San	207	3.94	3.37 (2.43, 4.66)	3.14 (2.26, 4.37)
Zou-Gui-Wan	152	2.89	2.69 (1.88, 3.85)	2.47 (1.71, 3.56)
Gui-Zhi-Fu-Ling-Wan	127	2.42	3.64 (2.38, 5.55)	3.27 (2.13, 5.02)
You-Gui-Wan	115	2.19	2.33 (1.56, 3.47)	2.12 (1.41, 3.18)
Shao-Fu-Zhu-Yu-Tang	115	2.19	2.64 (1.75, 3.99)	2.54 (1.67, 3.86)
Liu-Wei-Dihuang-Wan	78	1.48	2.75 (1.66, 4.55)	2.52 (1.51, 4.21)
Gui-Pi-Tang	74	1.41	1.98 (1.22, 3.21)	1.69 (1.04, 2.77)
Si-Wu-Tang	57	1.08	4.24 (2.19, 8.20)	4.25 (2.18, 8.30)
Western medicine
Clomiphene citrate/tamoxifen	1299	24.72	3.87 (3.37, 4.44)	3.76 (3.26, 4.34)
GnRH agonist/GnRH antagonist	2	0.04	—	—
Progesterone	290	5.52	3.34 (2.54, 4.39)	3.22 (2.44, 4.26)
Bromocriptine/cabergoline	147	2.80	3.06 (2.10, 4.46)	2.94 (2.00, 4.32)

OR: odd ratio; 95% CI: 95% confidence interval; TCM: traditional Chinese medicine; ; ; . #: number of users divided by the total sample size. Multivariate-adjusted for age at diagnosis, insured amount, urban level, residential area, insured unit, and comorbidities.