Efficacy and Safety of Chinese Herbal Formula Granules in Treating Chronic Kidney Disease Stage 3: A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial

Table 14

Change from baseline in urea nitrogen over the 24-week follow-up period.

Time	Treatment group	Control group	Effect	F value	value
Pretreatment (mmol/L)	8.75 ± 3.06	8.69 ± 2.69	Time effect	0.25	0.9388
Week 4 (mmol/L)	8.90 ± 2.68	8.24 ± 2.76	Difference between groups	4.26	0.0399
Week 8 (mmol/L)	9.02 ± 2.85	8.25 ± 2.61
Week 12 (mmol/L)	9.12 ± 2.75	8.22 ± 2.40
Week 16 (mmol/L)	8.94 ± 2.73	8.24 ± 2.25
Week 20 (mmol/L)	8.93 ± 2.72	8.34 ± 2.38
Week 24 (mmol/L)	8.76 ± 2.67	8.40 ± 2.54