Efficacy and Safety of Chinese Herbal Formula Granules in Treating Chronic Kidney Disease Stage 3: A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial

Table 5

Change from baseline in 24-hour proteinuria over the 24-week follow-up period.

Time	Treatment group	Control group	Effect	F value	value
Pretreatment (g/24 h)	0.72 ± 0.61	0.66 ± 0.58	Time effect	4.19	0.0009
Week 4 (g/24 h)	0.81 ± 0.83	0.72 ± 0.70	Difference between groups	3.10	0.0792
Week 8 (g/24 h)	0.82 ± 0.89	0.85 ± 1.16
Week 12 (g/24 h)	0.84 ± 1.01	1.01 ± 1.59
Week 16 (g/24 h)	0.81 ± 0.95	0.99 ± 1.39
Week 20 (g/24 h)	0.87 ± 1.02	1.01 ± 1.47
Week 24 (g/24 h)	0.97 ± 1.14	0.97 ± 1.25

Compared with pretreatment, the difference was significant in the control group,  < 0.05.