Research Article
A Network Pharmacology Approach to Explore the Mechanisms of Shugan Jianpi Formula in Liver Fibrosis
Table 2
Common target gene dimension ranking.
| | Genes | Degree |
| | IL6 | 45 | | TP53 | 40 | | PTGS2 | 39 | | AKT1 | 38 | | TNF | 37 | | IL1β | 35 | | NFKB1 | 34 | | F2 | 34 | | IL4 | 30 | | NOS3 | 30 | | IL2 | 28 | | PPARG | 28 | | IGF1 | 28 | | IFNG | 27 | | NOS2 | 27 | | EDN1 | 27 | | CSF2 | 26 | | ESR1 | 25 | | VCAM1 | 25 | | NFKBIA | 24 | | CRP | 24 | | PPARA | 24 | | MPO | 23 | | NR3C1 | 23 | | NOS1 | 22 | | CYP3A4 | 20 | | FASLG | 20 | | CD40 | 20 | | ADIPOQ | 19 | | IKBKB | 17 | | ABL1 | 16 | | PTGS1 | 16 | | CYP1A1 | 15 | | CHUK | 14 | | TBX21 | 11 | | S100A8 | 10 | | AKR1C3 | 10 | | PGR | 10 | | VDR | 10 | | NR1I2 | 9 | | ACSL1 | 9 | | CNR1 | 8 | | MT-CO2 | 9 | | ABCB1 | 8 | | MPL | 8 | | ALDH2 | 7 | | CYP27B1 | 7 | | HCK | 7 | | S100A9 | 7 | | EDNRA | 6 | | NQO1 | 6 | | HSPA5 | 6 | | CYP4F2 | 5 | | HTR2A | 5 | | GC | 5 | | CYP2R1 | 5 | | MT-CO1 | 4 | | PLCB1 | 4 | | IL18R1 | 4 | | ACADM | 4 | | PPARD | 4 | | MTTP | 4 | | NR1H4 | 4 | | PLA2G2E | 4 | | ALK | 4 | | DRD2 | 3 | | DRD4 | 3 | | ABCB11 | 3 | | AKR1C2 | 3 | | CNR2 | 3 | | ABCC8 | 3 | | SRD5A1 | 2 | | SPARC | 2 | | COX8A | 2 | | IVD | 2 | | ACVRL1 | 2 | | PFKL | 1 | | STX1A | 1 | | KCNA5 | 1 | | TPMT | 1 | | ANK2 | 1 | | ADH1B | 1 | | PAH | 1 | | GJA5 | 1 |
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