The Essential Oil from Acori Tatarinowii Rhizome (the Dried Rhizome of Acorus tatarinowii Schott) Prevents Hydrogen Peroxide-Induced Cell Injury in PC12 Cells: A Signaling Triggered by CREB/PGC-1α Activation

Figure 3

ATEO suppressed ROS production in H₂O₂-stressed PC12 cells. (a) PC12 cells were exposed to H₂O₂ (0–600 μM) for 1 h The level of intracellular ROS was measured. (b) PC12 cells were pre-treated with ATEO (1.5, 5 and 15 μg/mL) for 48 h and then exposed to H₂O₂ (400 μM) for 1 h. ZLN005 (2 μM) was used as a positive control. The results were in % of control (untreated culture). Data are expressed as mean ± SEM, n = 3. , compared with the control group; , compared with the H₂O₂-treated group.

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(b)