An Efficacy Predictive Method for Diabetic Ulcers Based on Higher-Order Markov Chain-Set Pair Analysis
Table 4
Index levels at each time point of 15 patients.
Index
t0
t1
t2
t3
t4
t0
t1
t2
t3
t4
t0
t1
t2
t3
t4
Patient a
Patient b
Patient c
K1
IV
III
II
II
II
IV
III
II
II
II
III
II
II
II
II
K2
IV
II
II
I
II
V
IV
III
II
II
IV
III
II
I
II
K3
III
II
I
I
I
IV
III
II
II
II
II
I
I
I
I
K4
III
I
I
I
I
II
I
I
I
I
IV
III
II
II
II
K5
II
II
I
I
I
III
II
II
I
II
II
I
I
I
I
K6
IV
III
II
I
II
IV
III
II
I
II
IV
III
II
II
II
K7
V
IV
III
II
II
V
III
II
II
II
V
IV
III
II
II
K8
III
I
I
I
I
III
II
I
I
I
III
II
II
I
I
K9
V
IV
III
II
II
III
II
I
II
II
IV
III
III
III
III
K10
V
IV
II
II
II
III
II
I
I
I
IV
III
III
II
II
Patient d
Patient e
Patient f
K1
IV
III
II
II
II
IV
III
II
II
II
III
II
II
II
II
K2
III
II
II
II
II
V
IV
III
II
II
V
IV
III
III
III
K3
II
I
I
I
I
IV
III
II
I
II
II
I
I
I
I
K4
II
II
I
I
I
II
I
I
I
I
IV
III
II
II
II
K5
III
II
I
I
I
III
II
I
I
II
II
I
I
I
I
K6
IV
III
II
I
II
IV
III
II
I
II
IV
III
II
II
II
K7
V
IV
III
II
II
IV
III
III
II
II
V
IV
III
II
III
K8
III
I
I
I
I
II
I
I
I
I
III
III
II
I
I
K9
V
III
II
II
II
IV
III
III
II
II
IV
III
II
I
II
K10
V
IV
IV
III
III
III
II
II
I
I
III
III
II
II
II
Patient g
Patient h
Patient i
K1
V
IV
III
III
III
IV
II
II
I
I
IV
III
II
I
II
K2
V
III
III
II
II
III
II
I
I
I
V
III
I
I
I
K3
IV
III
II
II
II
II
I
I
I
I
III
II
I
I
I
K4
II
II
I
I
I
III
II
I
I
I
II
I
II
I
I
K5
III
III
II
I
I
II
I
I
I
I
III
I
I
I
I
K6
IV
III
IV
III
III
V
IV
III
III
III
IV
III
III
II
II
K7
V
IV
IV
III
IV
IV
III
III
II
II
V
IV
IV
III
IV
K8
II
I
I
I
I
II
I
I
I
I
II
I
I
I
I
K9
IV
IV
III
II
III
IV
III
IV
III
III
IV
IV
III
II
III
K10
IV
III
II
I
II
V
IV
IV
III
IV
IV
III
II
II
II
Patient j
Patient k
Patient l
K1
IV
III
II
II
II
III
II
I
I
I
V
IV
III
III
III
K2
III
II
I
I
I
III
II
I
I
I
IV
III
II
I
II
K3
II
II
I
I
I
II
II
II
I
I
III
II
I
I
I
K4
III
I
I
I
I
II
I
I
I
I
III
I
I
I
I
K5
II
II
I
I
I
II
II
II
I
I
II
II
I
I
I
K6
IV
III
II
I
II
III
II
I
I
I
IV
III
II
II
II
K7
V
IV
III
II
III
IV
III
III
II
III
V
IV
III
II
II
K8
III
I
II
I
I
III
III
II
I
II
III
I
I
I
I
K9
V
IV
III
III
III
V
IV
III
II
III
V
III
IV
III
III
K10
V
IV
II
II
II
III
III
II
II
II
IV
IV
III
II
III
Patient m
Patient n
Patient o
K1
IV
III
II
II
II
III
II
II
I
I
III
III
II
II
II
K2
III
III
II
II
II
IV
III
IV
III
III
IV
IV
IV
III
III
K3
III
II
I
I
I
IV
IV
III
III
III
II
I
I
I
I
K4
IV
III
II
II
II
II
I
I
I
I
IV
III
II
II
I
K5
III
I
I
I
I
III
II
II
I
II
II
I
I
I
I
K6
V
IV
III
III
IV
IV
III
III
II
III
IV
III
II
I
II
K7
IV
III
IV
III
II
IV
III
II
II
II
V
IV
III
II
III
K8
V
III
II
II
II
III
II
I
I
I
III
II
II
I
II
K9
III
II
II
I
II
IV
III
III
II
II
IV
III
III
II
II
K10
III
III
II
I
II
III
II
II
I
I
III
III
II
I
I
The symptom index levels of patients a–o at five time points were obtained by evaluation after every treatment course in the study. Levels I, II, III, IV, and V were asymptomatic, lighter, moderate, heavier, and severe, respectively.