Aloe-Emodin Induces Breast Tumor Cell Apoptosis through Upregulation of miR-15a/miR-16-1 That Suppresses BCL2

Figure 1

Effects of AE on cells proliferation. (a) MCF-10A, MCF-10AT, MCF-7, and MDA-MB-231 cells were treated with increasing doses of AE (0–100 μM) for 72 h incubation. MCF-10AT (b) and MCF-7 (c) cells were treated with increasing doses of AE (0–100 μM) for 24 h, 48 h, and 72 h incubation. The data of cells viability were shown as mean ± SD of three independent experiments, .

(a)

(b)

(c)