Review Article
Xinmailong Injection for Improvement of Cardiac Function in Patients with Heart Failure: A Systematic Review and Meta-Analysis
Table 3
Mean difference of cardiac function of HF patients with XML injection administration in different subgroup analyses.
| | | LVEF | 6MWT | BNP | | N | WMD (95% CI) | I2 (%) | value for between-group difference | N | WMD (95% CI) | I2 (%) | value for between-group difference | N | WMD (95% CI) | I2 (%) | value for between-group difference |
| | Overall | 27 | 5.82 (4.52, 7.13) | 90 | | 15 | 51.48 (35.83, 67.13) | 88 | | 16 | −172.84 (−205.79, −139.89) | 94 | | | Subgroups | | | | | | | | | | | | | | Age section | | | | 0.006 | | | | 0.0002 | | | | 0.01 | | Youth | 11 | 4.11 (2.61, 5.62) | 83 | | 6 | 34.58 (21.26, 47.89) | 61 | | 5 | −156.70 (−201.26, −112.15) | 88 | | | Middle age | 11 | 7.70 (5.60, 9.79) | 90 | | 5 | 77.39 (58.94, 95.84) | 77 | | 6 | −301.54 (−405.38, −197.71) | 97 | | | Pattern identification | | | | 0.88 | | | | 0.72 | | | | 0.37 | | Yes | 4 | 5.68 (3.83, 7.53) | 33 | | 3 | 60.60 (−1.01, 122.21) | 87 | | 3 | −243.87 (−426.98, −60.76) | 97 | | | No | 23 | 5.87 (4.38, 7.36) | 90 | | 12 | 48.88 (34.52, 63.24) | 84 | | 13 | −159.10 (−193.30, −124.89) | 94 | |
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LVEF, left ventricular ejection fraction; 6MWT, six-minute walk test; BNP, brain natriuretic peptide; WMD, weighted mean difference; CI, confidence interval.
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