Hepatoprotective Effects of Aqueous Extract of Opilia celtidifolia (Opiliaceae) Leaves against Ethanol-Induced Liver Damage in Rats
Table 4
Effects of O. celtidifolia on some parameters of liver function.
Parameters
Normal control
Negative control (H2O, 5 ml/kg)
Positive control (silymarin 100 mg/kg)
O. celtidifolia (100 mg/kg)
O. celtidifolia (200 mg/kg)
O. celtidifolia (400 mg/kg)
ALT (UI/l)
56.43 ± 3.42
76.83 ± 4.19###
39.4 ± 7.12
38.79 ± 5.42
26.42 ± 4.52
48.03 ± 7.22
AST (UI/l)
115.99 ± 22
192.38 ± 26.33#
125.5 ± 13.58
108.00 ± 8.19
80.5 ± 6.54##
120.54 ± 11.31
ALP (UI/l)
65.76 ± 7.31
88.38 ± 14.56#
82.51 ± 17.01
43.7 ± 3.02
42.10 ± 9.55
30.03 ± 5.28###
Total bilirubin (mg/dl)
4.3 ± 0.032
5.15 ± 0.65
4.1 ± 0.77
2.85 ± 0.64#
1.53 ± 0.28##
2.75 ± 0.47##
Conjugated bilirubin (mg/dl)
0.145 ± 0.01
0.47 ± 0.15
0.49 ± 0.04
0.64 ± 0.16
0.76 ± 0.085
0.81 ± 0.50
The values represent mean ± SEM, significant statistical differences compared to the negative control. ## significant statistical differences compared to the normal control.
