Research Article

The Therapeutic Effects of Goreisan, a Traditional Japanese Herbal Medicine, on Lower-Limb Lymphedema after Lymphadenectomy in Gynecologic Malignancies: A Case Series Study

Table 1

Patient characteristics stratified by the CDT group and CDT-G group.

Total (n = 19)CDT group (n = 8)CDT-G group (n = 11) value

Age (mean, 95% CI)56.4 (50.6–62.2)55.3 (46.1–64.5)57.3 (49.4–65.1)0.737
Duration to diagnosis (median, range)19.5 (4.2–243.1)40.1 (4.4–243.1)10.7 (4.2–162.1)0.386
Body mass index (mean, 95% CI)22.6 (20.6–24.6)23.3 (20.2–26.5)22.1 (19.4–24.8)0.535
Type of cancer (n, (%))0.965
Cervical cancer10 (52.6)4 (50.0)6 (54.5)
Endometrial cancer7 (36.8)3 (37.5)4 (36.4)
Ovarian cancer2 (10.5)1 (12.5)1 (9.1)
Type of lymphadenectomy (n, (%))0.830
PLN16 (84.2)7 (87.5)9 (81.8)
PLN + PAN3 (15.8)1 (12.5)2 (18.2)
Chemotherapy (n, (%))0.425
Yes15 (78.9)7 (87.5)8 (72.7)
No4 (21.1)1 (12.5)3 (27.3)
Radiotherapy (n, %)0.637
Yes6 (31.6)3 (37.5)3 (27.3)
No13 (68.4)5 (62.5)8 (72.7)
Affected side (n, (%))0.255
Left9 (47.4)5 (62.5)4 (36.4)
Right10 (52.6)3 (37.5)7 (63.6)

CDT, complex decongestive therapy; CDT-G, combination of complex decongestive therapy and goreisan; CI, confidence interval; PLN, pelvic lymphadenectomy; PAN, paraaortic lymphadenectomy.